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The next step of community health construction: Training general practitioners and implementing health

Kan ZHANG MM, Wei DONG MM, Ying-Yao CHEN MD,

《医学前沿（英文）》 2010年第4卷第2期页码 134-138 doi: 10.1007/s11684-010-0041-6

摘要： This article discusses the concept of health management and stresses that community health management should be the starting point of community health service, necessitating a paradigm shift from observing the treatment-oriented medical model to observing the prevention-and-health management-based medical model. Community health construction has entered a new phase, one which highlights the need to train general practitioners in practice-based life cycle health management. In addition, general practitioners should assume the mission of implementing community health management.

关键词： community health general practitioners health management

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A novel intravenous general anesthetic--- emulsified isoflurane: from bench to bedside

null

《医学前沿（英文）》 2012年第6卷第4期页码 381-387 doi: 10.1007/s11684-012-0229-z

摘要：

Application of volatile anesthetics greatly alters modern medicine. There are obvious advantages of volatile anesthetics such as strong anesthetic potency, rapid onset and elimination through respiration system. Isoflurane is one of the most widely used volatile anesthetics in clinic. Emulsified isoflurane, the emulsion of isoflurane, is a novel intravenous general anesthetic. With the development of emulsified isoflurane in the past fifteen years, its utility has spread from intravenous general anesthesia to various fields including regional anesthesia, organ protection, as well as anesthetic pharmacological study. In this review, we will summarize literatures of emulsified isoflurane about its history, clinical application and future potential utility in the above mentioned fields.

关键词： emulsified isoflurane (EI) general anesthesia regional anesthesia organ protection anesthetic pharmacological study

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Numerical investigation of circle defining curve for two-dimensional problem with general boundaries

Chung Nguyen VAN

《结构与土木工程前沿（英文）》 2019年第13卷第1期页码 92-102 doi: 10.1007/s11709-018-0472-8

摘要： The scaled boundary finite element method (SBFEM) is applied to the static analysis of two dimensional elasticity problem, boundary value problems domain with the domain completely described by a circular defining curve. The scaled boundary finite element equations is formulated within a general framework integrating the influence of the distributed body force, general boundary conditions, and bounded and unbounded domain. This paper investigates the possibility of using exact geometry to form the exact description of the circular defining curve and the standard finite element shape function to approximate the defining curve. Three linear elasticity problems are presented to verify the proposed method with the analytical solution. Numerical examples show the accuracy and efficiency of the proposed method, and the performance is found to be better than using standard linear element for the approximation defining curve on the scaled boundary method.

关键词： exact geometry circular defining curve general boundaries SBFEM

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coated on endotracheal tube with or without epidural lidocaine reduces isoflurane requirement during general

null

《医学前沿（英文）》 2012年第6卷第3期页码 302-306 doi: 10.1007/s11684-012-0194-6

摘要：

This study was designed to evaluate the effect of tracheal topical anesthesia using EMLA^? Cream (EC) coated on the endotracheal tube (ETT) with or without epidural anesthesia (EA) on isoflurane requirement during general anesthesia (GA) and investigate whether EC coated on the ETT with EA was associated with the additive effect compared with the effect when each anesthetic was administered independently. The prospective randomized, double-blinded, and controlled study included 60 ASA I–II patients scheduled for upper abdominal surgery requiring GA. Patients were randomly assigned to one of the following groups: group 1 received GA, group 2 received EC+ GA, group 3 received GA+ EA, and group 4 received EC+ GA+ EA. Isoflurane was administered at the required concentrations to maintain the mean arterial pressure at a level not exceeding 20% of preoperative values. The percentage mean expired concentration (%MEC) was used in calculating the isoflurane requirement. Emergence agitation, postoperative sore throat, and hoarseness were recorded. Groups 2, 3, and 4 exhibited a significant reduction on isoflurane requirement compared with group 1 (P<0.05). The isoflurane requirement evaluated by %MEC decreased by 12%, 38%, and 50% in groups 2, 3, and 4, respectively. The incidence of emergence agitation was significantly lower in groups 2 and 4 than those in groups 1 and 3 (P<0.05). Tracheal topical anesthesia using EC coated on ETT with or without EA reduced the isoflurane requirement during GA, indicating that EC combined with EA exhibited an additive effect on the requirement of general anesthetic.

关键词： EMLA? Cream epidural anesthesia general anesthesia isoflurane lidocaine

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声学综合无损检测技术

陈积懋

《中国工程科学》 2000年第2卷第4期页码 64-69

摘要：

论述了检测复合材料和胶接结构不连续（缺陷）的新型多模综合无损检测技术。该技术以声与超声检测技术为基础，包含五种不同检测模式，用以检测复合材料与胶接结构的失粘、脱粘、分层、疏松、夹芯压皱及其他缺陷。它适用于复合材料与构件的制造、维修和使用现场。它的适用对象范围广泛，几乎覆盖了现有常用的复合材料和胶接结构。它的检测可靠性高，重复精度好。文章还讨论了组成多膜声学综合胶接检测仪的五种不同检测模式的原理，并从我们和国内外同行的大量实践经验出发，说明了综合无损检测技术的巨大发展前景。

关键词：声学综合检测综合无损检测复合材料无损检测机械阻抗分析振动分析共振检测

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General modeling and optimization technique for real-world earth observation satellite scheduling

《工程管理前沿（英文）》页码 695-709 doi: 10.1007/s42524-023-0263-3

摘要： Over the last two decades, many modeling and optimization techniques have been developed for earth observation satellite (EOS) scheduling problems, but few of them show good generality to be engineered in real-world applications. This study proposes a general modeling and optimization technique for common and real-world EOS scheduling cases; it includes a decoupled framework, a general modeling method, and an easy-to-use algorithm library. In this technique, a framework that decouples the modeling, constraints, and optimization of EOS scheduling problems is built. With this framework, the EOS scheduling problems are appropriately modeled in a general manner, where the executable opportunity, another format of the well-known visible time window per EOS operation, is viewed as a selectable resource to be optimized. On this basis, 10 types of optimization algorithms, such as Tabu search and genetic algorithm, and a parallel competitive memetic algorithm, are developed. For simplified EOS scheduling problems, the proposed technique shows better performance in applicability and effectiveness than the state-of-the-art algorithms. In addition, a complicatedly constrained real-world benchmark exampled by a four-EOS Chinese commercial constellation is provided, and the technique is qualified and outperforms the in-use scheduling system by more than 50%.

关键词： earth observation satellite scheduling general technique optimization algorithm commercial constellation real-world benchmark

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Feasible workspace regions for general two-revolute manipulator

Conghui LIANG, Marco CECCARELLI

《机械工程前沿（英文）》 2011年第6卷第4期页码 397-408 doi: 10.1007/s11465-011-0228-9

摘要：

In this paper, a topology is presented for feasible workspace regions in general two-revolute manipulators. The design problem and concept of feasible workspace regions have been discussed as linked to each other. Design equations are formulated by arbitrarily prescribing four workspace boundary points. The so-called feasible workspace regions are the intersection of three different sub-regions, which are given by constraint curves as function of the relative positions of three workspace boundary points. By using a parametric study, all topologies for three sub-regions are figured out. Corresponding areas in cross section plane are determined for prescribing the position of a feasible workspace point as function of the topology for sub-regions. A classification has been proposed to determine and to characterize the combination of the topologies for those sub-regions. All topologies for feasible workspace regions are figured out and they are discussed as a design tool. Three general cases are analyzed in details to characterize workspace design capabilities for general two-revolute manipulators.

关键词： workspace two-revolute manipulators topology analysis design

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General framework for bridge life cycle design

Junhai MA, Airong CHEN, Jun HE

《结构与土木工程前沿（英文）》 2009年第3卷第1期页码 50-56 doi: 10.1007/s11709-009-0004-7

摘要： Based on a detailed illustration for bridge life cycle design which comprises the processes of service life design, aesthetics design, performance design, environmental and ecological design, inspection, maintenance and repair design as well as cost analysis, this paper presented a general framework for bridge life cycle design comprising three design phases and six design processes.

关键词： bridge whole life design design phase design process general framework

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卫星移动网络总体概念设计仿真

金士尧

《中国工程科学》 2004年第6卷第1期页码 30-36

摘要：

卫星移动网络是以卫星星座为基本物理架构，通过星际的通信链路形成覆盖全球的天基通信网络。它对社会发展、科技进步以及军队的信息化有着重大的推动作用。由于天网的移动性、通信的偶断性、接入的复杂性以及使用的综合性，都为研制提出了重大的挑战。有必要通过总体概念设计仿真，来进一步验证总体需求、总体方案、关键技术指标和研制的约束条件，形成科学的可行性报告。介绍了卫星移动网络的总体概念，设计了针对天网仿真的平台，并用实例获得卫星移动网络总体概念设计的仿真数据。

关键词：卫星移动网络总体仿真

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pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry during general

null

《医学前沿（英文）》 2012年第6卷第4期页码 406-410 doi: 10.1007/s11684-012-0217-3

摘要：

The esophagus is perfused directly by prominent arteries and may provide a more consistent tissue source for pulse oximetry. The goal of this study was to evaluate the sensitivity and accuracy of an esophageal pulse oximetry probe on patients during controlled hypoxemia in comparison to measurements obtained with conventional pulse oximetry (SpulseO₂). Forty-five ASA I–II adult patients were included in this prospective observational study. Nellcor digital oximetric probes were placed on finger tips for SpulseO₂ before anesthesia. After tracheal intubation, an esophageal probe was placed in the lower segment of the esophagus for esophageal oximetric monitoring (SoesO₂). All patients were disconnected from the breathing circuit to establish a controlled hypoxemia, and were re-connected to the breathing circuit and ventilated with 100% oxygen immediately when SoesO₂ dropped to 90%. Matched SoesO₂ and SpulseO₂ readings were recorded when SoesO₂measurements were at 100%, 95%, 90% and the lowest reading. The time for SoesO₂ and SpulseO₂ to drop from 100% to 95%, 90% and return to 100% was recorded. Oxygen saturation from arterial blood samples (SartO₂) was also measured at each time point respectively. The linear correlation coefficient of the regression analysis between SartO₂ and SoesO₂ was 0.954. The mean±2SD of the difference was 0.3%±4.3% for SoesO₂vs. SartO₂ and 6.8%±5.6% for SpulseO₂vs. SartO₂ (P<0.001). The 95% confidence interval for the absolute difference between SoesO₂ and SartO₂ was 0.3% to 0.7% and 6.2% to 7.4% between SpulseO₂ and SartO₂. The time to reach 90% saturation measured with SoesO₂ was approximately 94 seconds earlier than the SpulseO₂ (P<0.001). In conclusion, SoesO₂ is more accurate and enables earlier detection of hypoxemia when compared to conventional pulse oximetry during hypoxemia for patients undergoing general anesthesia.

关键词： esophageal pulse oximetry conventional pulse oximetry hypoxemia

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我国全科医生培养现状与发展策略

刘颖,蒋国平,任菁菁

《中国工程科学》 2019年第21卷第2期页码 74-78 doi: 10.15302/J-SSCAE-2019.02.005

摘要：

经过近30年的不断探索和实践，我国全科医生队伍建设取得了一定的进展，初步建立了以“5+3”为主、“3+2”为辅的全科医生培养模式，但我国仍面临严重缺乏合格全科医生的情况。本文通过对我国全科医生培养现状的研究，了解到当前我国全科医生岗位缺乏吸引力，全科医生培养制度和体系不够完善，缺乏完善的过程考核机制，住培基地准入和再认证机制不完善，持续职业发展教育亟待规范。通过对国际上主要国家发展全科医生经验的回顾研究，建议我国应当切实提升全科医生待遇；以“岗位胜任力”为导向，建立完善的全科医生培训过程考核体系；统一全科医生住培基地准入条件，建立常态化基地评估认证机制；设置全科持续职业发展教育基地。

关键词：全科医生人才培养岗位胜任力

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Effects of intracerebroventricular NMDA and non-NMDA receptor agonists or antagonists on general anesthesia

XU Aijun, TIAN Yuke, DUAN Shiming

《医学前沿（英文）》 2007年第1卷第2期页码 207-210 doi: 10.1007/s11684-007-0039-x

摘要： The effects of intracerebroventricular (icv) agonists and antagonists of -methyl--aspartate (NMDA) and alpha-amino-3-hydroxy 5-methyl-4-isoxazole-propionic acid (AMPA) receptors on the general anesthesia of propofol were studied. A total of 144 Kunming mice, male and female with body mass of (22?3) g, were used. Part One of the Experiment: a total of 104 Kunming mice, male and female, were randomly divided into 13 groups. Intracerebroventricular artificial cerebral fluid (aCSF) or different doses of NMDA, AMPA, MK-801 or NBQX was injected immediately after intravenously administered propofol 25 mg/kg and the recovery time following the loss of righting reflex (LORR) was recorded. Part Two of the Experiment: a total of 40 Kunming female mice were divided randomly into 5 groups and injected with icv aCSF or NMDA, AMPA, MK-801 or NBQX after intraperitoneally administered propofol 50 mg/kg. The pain threshold of the mice was then investigated by hot-plate test (HPPT). NMDA (0.05 or 0.075?g, icv) or AMPA (0.05 ?g, icv) exhibited no effects on the LORR, but NMDA (0.1 μg, icv) or AMPA (0.075 or 0.1 ?g, icv) prolonged the LORR significantly compared with the aCSF group (<0.05, <0.01). The LORR of the 2 μg MK-801 group had no changes, while those of the 4 or 8 μg MK-801 groups were prolonged significantly. The LORR of the 0.5, 2 or 4 μg NBQX groups were all prolonged significantly. NMDA 0.05 ?g or AMPA 0.05 ?g decreased the pain threshold slightly but did not differ in effect compared with the aCSF group; 2 μg MK-801 or 0.5 μg NBQX both increased the pain threshold significantly. Our results indicate that propofol produces general anesthesia partly through an interaction with brain NMDA and AMPA receptors in mice.

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High-precision standard enthalpy of formation for polycyclic aromatic hydrocarbons predicting from general

《化学科学与工程前沿（英文）》 2022年第16卷第12期页码 1743-1750 doi: 10.1007/s11705-022-2184-9

摘要： The standard enthalpy of formation is an important predictor of the reaction heat of a chemical reaction. In this work, a high-precision method was developed to calculate accurate standard enthalpies of formation for polycyclic aromatic hydrocarbons based on the general connectivity based hierarchy (CBH) with the discrete correction of atomization energy. Through a comparison with available experimental findings and other high-precision computational results, it was found that the present method can give a good description of enthalpy of formation for polycyclic aromatic hydrocarbons. Since CBH schemes can broaden the scope of application, this method can be used to investigate the energetic properties of larger polycyclic aromatic hydrocarbons to achieve a high-precision calculation at the CCSD(T)/CBS level. In addition, the energetic properties of CBH fragments can be accurately calculated and integrated into a database for future use, which will increase computational efficiency. We hope this work can give new insights into the energetic properties of larger systems.

关键词： standard enthalpy of formation polycyclic aromatic hydrocarbons connectivity based hierarchy high-precision calculation

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中国优秀博硕士学位论文全文数据库（CDMD）总体介绍

《中国工程科学》 2002年第4卷第8期页码 94-94

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智能制造总体架构探析

孟柳,延建林,董景辰,韦莎,李瑞琪,臧冀原,周源

《中国工程科学》 2018年第20卷第4期页码 23-28 doi: 10.15302/J-SSCAE-2018.04.005

摘要：

智能制造是一个不断演进的大系统，涵盖了产品、制造、服务全生命周期中所涉及的理论、方法、技术和应用。面对智能制造不断涌现的新技术、新理念、新模式，迫切需要总结提出智能制造系统架构，以更好地指导智能制造落地实施。本文从价值维、技术维和组织维三个维度构建了中国智能制造总体架构，并分别与美国、德国、日本智能制造相关系统架构做了横向比较。智能制造总体架构的技术维反映了智能制造以两化融合为主线，价值维体现了智能制造的主体是制造活动，组织维强调了智能制造要以人为本。

关键词：智能制造总体架构智能转型优化升级